Adenine phosphoribosyltransferase
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adenine phosphoribosyltransferase
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| Identifiers | |
| Symbol | APRT |
| HUGO | 626 |
| Entrez | 353 |
| OMIM | 102600 |
| RefSeq | NM_000485 |
| UniProt | P07741 |
| Other data | |
| EC number | 2.4.2.7 |
| Locus | Chr. 16 q24 |
Adenine phosphoribosyltransferase (or APRTase) is an enzyme involved in the purine nucleotide salvage pathway. It functions as a catalyst in the reaction between adenine and phosphoribosyl pyrophosphate (PRPP) to form AMP. APRTase is labeled as EC 2.4.2.7.
Deficiency of APRT in human beings may lead to kidney stones formed of adenine and salts. APRT is functionally related to HPRT.
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Hexosyltransferases: Glucosyltransferases (Glycogen branching enzyme, Glycogen synthase, Glycogen phosphorylase, Phosphorylase/Myophosphorylase) - Glucuronosyltransferase
Pentosyltransferases: Adenine phosphoribosyltransferase - Hypoxanthine-guanine phosphoribosyltransferase - ADP Ribose (Cholera toxin, Diphtheria toxin, Pertussis toxin, Poly ADP ribose polymerase)
