Carbonic anhydrase inhibitors
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Carbonic anhydrase inhibitors are a class of pharmaceuticals which, as their name implies, act as an enzyme inhibitor upon carbonic anhydrase.
[edit] Types
Acetazolamide is an inhibitor of carbonic anhydrase. It is used for glaucoma, epilepsy (rarely), benign intracranial hypertension, and altitude sickness. It can act as a mild diuretic by reducing NaCl and bicarbonate reabsorbtion in the proximal tubule. However, the distal segment partially compenates for the sodium loss, and the bicarbonaturia will produce a metabolic acidosis, further reducing the effect.
Methazolamide is also a carbonic anhydrase inhibitor. It is longer acting than acetazolamide and has less affect on the kidney[citation needed].
[edit] External links
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Competitive inhibition - Uncompetitive inhibition - Non-competitive inhibition - Suicide inhibition - Mixed inhibition
Acetylcholinesterase inhibitors - Aromatase inhibitors - Carbonic anhydrase inhibitors - Kinase inhibitors - Monoamine oxidase inhibitors - Reverse transcriptase inhibitors - Phosphodiesterase inhibitors - Protease inhibitors
