Choline acetyltransferase
From Wikipedia, the free encyclopedia
choline acetyltransferase
|
|
Identifiers | |
Symbol | CHAT |
HUGO | 1912 |
Entrez | 1103 |
OMIM | 118490 |
RefSeq | NM_020549 |
UniProt | P28329 |
Other data | |
EC number | 2.3.1.6 |
Locus | Chr. 10 q11.2 |
Choline acetyltransferase (EC 2.3.1.6) is an enzyme which is synthesized within the body of a neuron. It is then transferred to the nerve terminal via axoplasmic flow. It joins Acetyl CoA to choline, resulting in the formation of the neurotransmitter acetylcholine.
It is often used as a marker, immunohistochemically, for motor neurons (motoneurons).
[edit] See also
[edit] External links
Carnitine O-palmitoyltransferase - Glyceronephosphate O-acyltransferase - Lecithin-cholesterol acyltransferase - Citrate synthase
Acetyltransferases: Beta-galactoside transacetylase - Choline acetyltransferase - Chloramphenicol acetyltransferase - Histone acetyltransferase (P300/CBP)- N-Acetylglutamate synthase -
Serotonin N-acetyl transferase
Aminoacyltransferases: Peptidyl transferase - Transglutaminase (Tissue transglutaminase, Factor XIII)