Acrivastine

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Acrivastine
Systematic (IUPAC) name
(E)-3-{6-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl- prop-1-enyl]pyridin-2-yl}prop-2-enoic acid
Identifiers
CAS number	87848-99-5
ATC code	R06AX18
PubChem	5284514
Chemical data
Formula	C₂₂H₂₄N₂O₂
Mol. mass	348.438 g/mol
SMILES	search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	1.5 hours
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Acrivastine is a medication used for the treatment of allergies and hay fever. It is a second-generation H1-receptor antagonist antihistamine and works by blocking H1 histamine receptors.

It is sold under the brand name Benadryl Allergy Relief in the U.K. by Pfizer, not to be confused with Benadryl Once a Day, which is cetirizine and is also sold by Pfizer in the U.K. The packaging for each is clearly distinctive.

v • d • e Antihistamines (primarily R06)
Aminoalkyl ethers	Bromazine, Carbinoxamine, Clemastine, Chlorphenoxamine, Diphenylpyraline, Diphenhydramine, Doxylamine
Substituted alkylamines	Brompheniramine, Chlorphenamine, Dexbrompheniramine, Dexchlorpheniramine, Dimetindene, Pheniramine, Talastine
Substituted ethylene diamines	Chloropyramine, Histapyrrodine, Mepyramine, Methapyrilene, Pyribenzamine
Phenothiazine derivatives	Alimemazine, Hydroxyethylpromethazine, Isothipendyl, Mequitazine, Methdilazine, Oxomemazine, Promethazine
Piperazine derivatives	Buclizine, Cetirizine, Chlorcyclizine, Cinnarizine, Cyclizine, Hydroxyzine, Levocetirizine, Meclozine, Niaprazine, Oxatomide
Others for systemic use	Acrivastine, Antazoline, Astemizole, Azatadine, Azelastine, Bamipine, Cyproheptadine, Deptropine, Desloratadine, Ebastine, Epinastine, Ketotifen, Loratadine, Mebhydrolin, Mizolastine, Phenindamine, Pimethixene, Pyrrobutamine, Rupatadine, Terfenadine, Triprolidine
For topical use	Bamipine, Chloropyramine, Chlorphenoxamine, Clemastine, Dimetindene, Diphenhydramine, Isothipendyl, Mepyramine, Promethazine, Thenalidine
Antiallergic agents excluding corticosteroids	Antazoline, Azelastine, Fexofenadine
Other antiallergics	Emedastine, Epinastine, Ketotifen, Olopatadine