Arginase
From Wikipedia, the free encyclopedia
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| Arginase, drawn from PDB 1CEV. | |
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Liver arginase
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| Identifiers | |
| Symbol | ARG1 |
| HUGO | 663 |
| Entrez | 383 |
| OMIM | 608313 |
| RefSeq | NM_000045 |
| UniProt | P05089 |
| Other data | |
| EC number | 3.5.3.1 |
| Locus | Chr. 6 q23 |
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Arginase, type II
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| Identifiers | |
| Symbol | ARG2 |
| HUGO | 664 |
| Entrez | 384 |
| OMIM | 107830 |
| RefSeq | NM_001172 |
| UniProt | P78540 |
| Other data | |
| EC number | 3.5.3.1 |
| Locus | Chr. 14 q24.1 |
Arginase is a manganese-containing enzyme. The reaction catalyzed by this enzyme is: arginine + H2O → ornithine + urea. It is the final enzyme of the urea cycle.
[edit] Pathology
A lack of arginase can lead to a condition called "hyperargininemia" or arginemia.
[edit] External links
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Carbon-nitrogen non-peptide hydrolases (EC 3.5)
