GTP cyclohydrolase I
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GTP cyclohydrolase 1
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| Identifiers | |
| Symbol | GCH1 GCH, DYT5 |
| HUGO | 4193 |
| Entrez | 2643 |
| OMIM | 600225 |
| RefSeq | NM_000161 |
| UniProt | P30793 |
| Other data | |
| EC number | 3.5.4.16 |
| Locus | Chr. 14 q22.1-22.2 |
GTP cyclohydrolase I (GTP 7,8-8,9-dihydrolase, EC 3.5.4.16) is an enzyme that is part of the folate and biopterin biosynthesis pathways. It is responsible for the hydrolysis of guanosine triphosphate (GTP) to form 7,8-dihydroneopterin 3'-triphosphate.
[edit] References
- Voet, D.; Voet, J.G. (2004). Biochemistry (3rd ed.). John Wiley & Sons. ISBN 0-471-39223-5
- EC 3.5.4.16 IUBMB Enzyme Nomenclature
[edit] External links
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Carbon-nitrogen non-peptide hydrolases (EC 3.5)
