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Benperidol

From Wikipedia, the free encyclopedia

Benperidol
Systematic (IUPAC) name
1-[1-[4-(4-fluorophenyl)-4-oxo-butyl]-4-piperidyl]-3H-benzoimidazol-2-one
Identifiers
CAS number 983-42-6
ATC code  ?
PubChem 16363
Chemical data
Formula C22H24FN3O2 
Mol. mass 381.443g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Oral

Benperidol is a drug which is a butyrophenone derivative. It is an antipsychotic, which can be used for the treatment of schizophrenia[1], but it is primarily used to control deviant, antisocial hypersexual behaviour[2], and is sometimes prescribed to sex offenders as a condition of their parole, as an alternative to anti-androgen drugs such as cyproterone.[3]

Benperidol was discovered at Janssen Pharmaceutica in 1961.

[edit] References

  1. ^ Bobon J, Collard J, Lecoq R, Benperidol and promazine: a "double blind" comparative study in mental geriatrics, Acta Neurol Belg. 1963 Oct;63:839-43.
  2. ^ British National Formulary (49th), British Medical Association 2005 p 183
  3. ^ Murray MA, Bancroft JH, Anderson DC, Tennent TG, Carr PJ., Endocrine changes in male sexual deviants after treatment with anti-androgens, oestrogens or tranquillizers, Journal of Endocrinology. 1975 Nov;67(2):179-88.


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