Keratin 18
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keratin 18
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Identifiers | |
Symbol | KRT18 |
HUGO | 6430 |
Entrez | 3875 |
OMIM | 148070 |
RefSeq | NM_199187 |
UniProt | P05783 |
Other data | |
Locus | Chr. 12 q13 |
Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.