Type II cytokeratin
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Type II cytokeratins constitutes the Type II intermediate filaments (IFs) of the intracytoplasmatic cytoskeleton, which is present in all mammalian epithelial cells. The type 2 cytokeratins consist of basic or neutral, high molecular weight proteins which 'in vivo' are arranged in pairs of heterotypic Type I and Type II keratin chains, coexpressed during differentiation of simple and stratified epithelial tissues.
Type II cytokeratins are encoded on chromosome 12q and encompasses: CK1, CK2, CK3, CK4, CK5, CK6, CK7 and CK8. Their molecular weight ranges from 52 kDa (CK8) to 67 kDa (CK18).
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Microfilaments: Actins - Myosins - Actin-binding proteins
Intermediate filaments: type 1 and 2 Cytokeratin (type I, type II)
type 3 Desmin, GFAP, Peripherin, Vimentin
type 4 Internexin, Nestin, Neurofilament
type 5 Lamin (A, B)
Microtubules: Dyneins - Kinesins - MAPs (Tau protein) - Tubulins
Prokaryotic cytoskeleton: Crescentin - FtsZ - MreB
Other: Major Sperm Proteins
