Tolfenamic acid
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Tolfenamic acid
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| Systematic (IUPAC) name | |
| 2-[(4-chloro-3-methyl-phenyl)amino]benzoic acid | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C14H12ClNO2 |
| Mol. mass | 261.707 |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | oral |
Tolfenamic acid (TA) is one of the class of non steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.
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[edit] Other possible uses
- A study concludes, "TA was found significantly better than placebo in the subjective evaluation of drug efficacy (p<0.001) and in reducing the reported hangover symptoms in general (p < 0.01). In the TA group, significantly lower symptom scores were obtained for headache (p<0.01), and for nausea, vomiting, irritation, tremor, thirst and dryness of mouth (all p < 0.05)."[1]
[edit] Commercial names
Commercial names for tolfenamic acid include:
[edit] External links
[edit] References
- ^ S. Kaivola1, J. Parantainen, T. Österman and H. Timonen Hangover headache and prostaglandins: Prophylactic treatment with tolfenamic acid Cephalalgia Volume 3 Page 31 - March 1983 doi:10.1046/j.1468-2982.1983.0301031.x
Salicylates: Aspirin (Acetylsalicylic Acid), Diflunisal, Ethenzamide
Arylalkanoic acids: Diclofenac, Indometacin, Sulindac
2-Arylpropionic acids (profens): Carprofen, Flurbiprofen, Ibuprofen, Ketoprofen, Ketorolac, Loxoprofen, Naproxen, Tiaprofenic acid
N-Arylanthranilic acids (fenamic acids): Mefenamic acid
Pyrazolidine derivatives: Phenylbutazone
Coxibs: Celecoxib, Etoricoxib, Parecoxib, Rofecoxib, Valdecoxib
Sulphonanilides: Nimesulide
Topically used products: Diclofenac, Flurbiprofen, Ibuprofen, Indometacin, Ketoprofen, Naproxen, Piroxicam
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