Fenoldopam
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Fenoldopam
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| Systematic (IUPAC) name | |
| 8-chloro-2-(4-hydroxyphenyl)- 4-azabicyclo[5.4.0] undeca-7,9,11-triene-9,10-diol | |
| Identifiers | |
| CAS number | |
| ATC code | C01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C16H16ClNO3 |
| Mol. mass | 305.756 g/mol |
| Pharmacokinetic data | |
| Bioavailability | n/a |
| Metabolism | Hepatic (CYP not involved) |
| Half life | 5 minutes |
| Excretion | Renal (90%) and fecal (10%) |
| Therapeutic considerations | |
| Licence data |
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| Pregnancy cat. |
B(US) |
| Legal status | |
| Routes | Intravenous |
Fenoldopam is a synthetic compound that acts as a selective peripheral dopamine D1A receptor agonist. Fenoldopam is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation, decreasing afterload and also through specific dopamine receptors along the nephron promoting sodium excretion.
Dobutamine, Dopamine, Epinephrine, Fenoldopam, Isoprenaline, Metaraminol, Midodrine, Norepinephrine, Octopamine, Phenylephrine
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