Melatonin receptor
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melatonin receptor 1A
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| Identifiers | |
| Symbol | MTNR1A |
| HUGO | 7463 |
| Entrez | 4543 |
| OMIM | 600665 |
| RefSeq | NM_005958 |
| UniProt | P48039 |
| Other data | |
| Locus | Chr. 4 q35.1 |
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melatonin receptor 1B
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| Identifiers | |
| Symbol | MTNR1B |
| HUGO | 7464 |
| Entrez | 4544 |
| OMIM | 600804 |
| RefSeq | NM_005959 |
| UniProt | P49286 |
| Other data | |
| Locus | Chr. 11 q21-q22 |
A melatonin receptor is a G protein-coupled receptor which binds melatonin. [1]
There are two known varieties in humans: MT1 (or MTNR1A), and MT2 (or MTNR1B).[2]
They can be found in neuroendocrine tissues such as the pars tuberalis of the pituitary gland and the suprachiasmatic nuclei of the hypothalamus.
[edit] See also
[edit] References
- ^ Reppert S (1997). "Melatonin receptors: molecular biology of a new family of G protein-coupled receptors.". J Biol Rhythms 12 (6): 528-31. PMID 9406026.
- ^ MeSH Melatonin+Receptors
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Adenosine - Adrenergic - Angiotensin - Bradykinin - Calcitonin - Cannabinoid - Chemokine - Cholecystokinin - Corticotropin-releasing hormone - Dopamine - Endothelin - FSH-receptor - GABA B - Galanin - Glucagon - Gonadotropin-releasing hormone - Histamine (H1, H2, H3, H4) - Luteinizing hormone/choriogonadotropin - Melanocortin (MC1R, MC2R) - Melatonin - Metabotropic glutamate - Muscarinic acetylcholine - Neurotensin - Olfactory - Opioid (Delta, Kappa, Mu, Sigma, Nociceptin) - Parathyroid hormone - Purinergics (P2Y) - Trace amine-associated - Secretin - Serotonin, all but 5-HT3 (5-HT2A)
