URB597
From Wikipedia, the free encyclopedia
urb597 | |
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Chemical name | (3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl) -cyclohexylcarbamate |
Chemical formula | C20H22N2O3 |
Molecular mass | 338.4 g/mol |
CAS number | 546141-08-6 |
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URB597 is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH). FAAH is the primary degradatory enzyme for the endocannabinoid anandamide and, as such, inhibition of FAAH leads to an accumulation of anandamide in the CNS and periphery. In pre-clinical laboratory tests researchers found URB597 increased the production of endocannabinoids resulting in measurable antidepressant effects.
URB597 is also known as KDS-4103. KDS-4103 is being developed by Kadmus Pharmaceuticals, Inc. for clinical trials in humans. Kadmus claims, on their website (linked below) that this class of compounds may have antidepressant, anti-anxiety, and pain-killing effects.
[edit] External links
- Kadmus Pharmaceuticals official website
- Modulation of anxiety through blockade of anandamide hydrolysis in Nature
- New drug acts as marijuana in the brain at cannabis.net
- Product Information from Cayman Chemical
Anandamide • 2-AG • CBD • CBDV • CBN • CBV • CP 55,940 • HU-210 • Levonantradol • JWH-133 • Nabilone • THC • THCV • URB597 • URB754 • WIN 55,212-2 • Rimonabant • AM251 • THC-O-phosphate • Parahexyl