Cefixime

From Wikipedia, the free encyclopedia

Cefixime
Systematic (IUPAC) name
(6R,7R)-7-{[2-(2-amino-1,3-thiazol-4-yl)-2-(carboxy methoxyimino)acetyl]amino}-3-ethenyl-8-oxo-5-thia- 1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Identifiers
CAS number	79350-37-1
ATC code	J01DD08
PubChem	54362
DrugBank	APRD00583
Chemical data
Formula	C16H15N5O7S2
Mol. mass	453.452 g/mol
Pharmacokinetic data
Bioavailability	40% to 50%
Protein binding	Approximately 60%
Metabolism	?
Half life	Variable Average 3 to 4 hours
Excretion	Renal and biliary
Therapeutic considerations
Pregnancy cat.	B
Legal status
Routes	Oral

Cefixime is an oral third generation cephalosporin antibiotic. It was sold under the trade name Suprax in the USA, until 2003 when it was taken off the market by drug manufacturer Wyeth after its patent expired. Cefixime is still available in Canada. It is used to treat gonorrhea.

[edit] External links

• Suprax Online - Information about cefixime.
• Notice to Readers: Discontinuation of Cefixime Tablets --- United States - A FDA report alerting physicians about the discontinuation of cefixime.

v • d • e Cephalosporin Antibiotics (J01D)
First Generation	Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole
Second Generation	Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam
Third Generation	Cefcapene, Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef
Fourth Generation	Cefclidine, Cefepime, Cefetecol,Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome