Meninges

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Meninges

Meninges of the CNS
Gray's	subject #193 872
Artery	middle meningeal artery, meningeal branches of the ascending pharyngeal artery, accessory meningeal artery, branch of anterior ethmoidal artery, meningeal branches of vertebral artery
Nerve	middle meningeal nerve, nervus spinosus
MeSH	Meninges
Dorlands/Elsevier	m_09/12523818

The meninges (singular meninx) is the system of membranes that envelop the central nervous system. The meninges consist of three layers: the dura mater, the arachnoid mater, and the pia mater. The primary function of the meninges and of the cerebrospinal fluid is to protect the central nervous system.

1 Anatomy
2 Pathology
3 Additional images
4 References

[edit] Anatomy

[edit] Pia mater

The pia or pia mater is a very delicate membrane. It is attached to, (nearest) the brain or the spinal cord. As such it follows all the minor contours of the brain (gyri and sulci). The pia mater is the meningeal envelope that firmly adheres to the surface of the brain and spinal cord. It is a very thin membrane composed of fibrous tissue covered on its outer surface by a sheet of flat cells thought to be impermeable to fluid. The pia mater is pierced by blood vessels that travel to the brain and spinal cord, and its capillaries are responsible for nourishing the brain.

[edit] Arachnoid mater

The middle element of the meninges is the arachnoid mater, so named because of its spider web-like appearance. It provides a cushioning effect for the central nervous system. The arachnoid mater exists as a thin, transparent membrane. It is composed of fibrous tissue and, like the pia mater, is covered by flat cells also thought to be impermeable to fluid. The arachnoid does not follow the convolutions of the surface of the brain and so looks like a loosely fitting sac. In the region of the brain, particularly, a large number of fine filaments called arachnoid trabeculae pass from the arachnoid through the subarachnoid space to blend with the tissue of the pia mater.

The arachnoid and pia mater are sometimes together called the leptomeninges.

[edit] Dura mater

The dura mater is a thick, durable membrane, closest to the skull. It contains larger blood vessels that split into the capilliaries in the pia mater. It is composed of dense fibrous tissue, and its inner surface is covered by flattened cells like those present on the surfaces of the pia mater and arachnoid. The dura mater is a sac that envelops the arachnoid and has been modified to serve several functions. The dura mater surrounds and supports the large venous channels (dural sinuses) carrying blood from the brain toward the heart.

[edit] Spaces

The subarachnoid space is the space that normally exists between the arachnoid and the pia mater, which is filled with cerebrospinal fluid.

Normally, the dura mater is attached to the skull in the head, or to the bones of the vertebral canal in the spinal cord. The arachnoid is attached to the dura mater, and the pia mater is attached to the central nervous system tissue. When the dura mater and the arachnoid separate through injury or illness, the space between them is the subdural space.

[edit] Pathology

There are three types of hemorrhage involving the meninges:^[1]

A subarachnoid hemorrhage is acute bleeding under the arachnoid; it may occur spontaneously or as a result of trauma.
A subdural hematoma is a hematoma (collection of blood) located in a separation of the arachnoid from the dura mater. The small veins that connect the dura mater and the arachnoid are torn, usually during an accident, and blood can leak into this area.
An epidural hematoma similarly may arise after an accident or spontaneously.

Other medical conditions that affect the meninges include meningitis (usually from fungal, bacterial, or viral infection) and meningiomas arising from the meninges or from tumors formed elsewhere in the body which metastasize to the meninges.