Portal:Molecular and Cellular Biology
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Welcome to the Molecular and Cellular Biology portal. Molecular biology is the study of biology at the molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Cell biology studies the properties of cells including their physiological properties, their structure, the organelles they contain, interactions with their environment, their life cycle, division and death. Molecular and cellular biology are interrelated, since most of the properties and functions of a cell can be described at the molecular level.
Molecular and Cellular Biology encompass many biological fields including: Biotechnology, Developmental Biology, Genetics and Microbiology.
Enzymes are proteins that catalyze (i.e. accelerate) chemical reactions. Enzymes are biochemical catalysts. In these reactions, the molecules at the beginning of the process are called substrates, and the enzyme converts these into different molecules, the products. Almost all processes in the cell need enzymes in order to occur at significant rates. Since enzymes are extremely selective for their substrates and speed up only a few reactions from among many possibilities, the set of enzymes made in a cell determines which metabolic pathways occur in that cell.
Endothelial cells under the microscope, stained to highlight its cytoskeleton. Nuclei are stained blue with DAPI, Microtubules are marked green by a FITC-conjugated antibody and actin filaments are labeled red with phalloidin
Rosalind Elsie Franklin (25 July 1920 – 16 April 1958) was an English physical chemist and crystallographer who made important contributions to the understanding of the fine structures of DNA, viruses, coal and graphite. Franklin is best known for her contribution to the discovery of the structure of DNA in 1953. In the years following, she led pioneering work on the tobacco mosaic and polio viruses. She died in 1958 of cancer of the ovary.
- ...that the cytoskeleton of a cell acts like a tensegrity model [1], such that a cell can resist shear, compression and tension.
- ...that eggs laid by the Ostrich can weigh 1.3 kg and the contained yolk is the largest single cell of any organism?
- ...that Red blood cells have an average life span of 120 days?
- ...that Robert Hooke coined the biological term cell -- so called because his observations of plant cells reminded him of monks' cells which were called "cellula"?
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Molecular and Cellular Biology
Branches of Molecular and Cellular Biology
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- 2007-03-20 ScienceNOW The secret to radiation-resistance in Deinococcus radiodurans may be manganese. more...
- 2007-03-15 ScienceNOW Gallium may have a use as an antimicrobial agent. Researchers at the University of Washington have seen therapeutically-promising results when Pseudomonas aeruginosa bacteria mistake gallium for iron. more...
- 2007-03-14 Science Bacterial Walls Come Tumbling Down. The publication of the Penicillin binding protein 2 crystal structure should improve antibiotic development. more...
- 2007-03-13 Science Daily Quinolones don't just kill bacterial via DNA gyrase inhibition, according to a group at Boston University, they also induce an artificial oxidative stress response. more...
Four stages of acceptance:
- i) this is worthless nonsense;
- ii) this is an interesting, but perverse, point of view;
- iii) this is true, but quite unimportant;
- iv) I always said so.
- —J. B. S. Haldane,Journal of Genetics (1963) 58:464.
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