Kromozom 10

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Kromozom 10, toplamda 22 çift olan otozomal insan kromozomlarından onuncusudur. İnsanlarda normalde bir çift halinde bulunur. 135 milyon baz çiftine ve toplam hücre DNA'sının %4 ya da %4,5'ine sahiptir. Kromozom 10, muhtemelen 800 ile 1,200 arasında gen içermektedir.

[değiştir] Genler

Kromozom 10 üzerinde bulunan genlerden bazıları:

• CDH23: cadherin-like 23
• EGR2: early growth response 2 (Krox-20 homolog, Drosophila)
• ERCC6: excision repair cross-complementing rodent repair deficiency, complementation group 6
• FGFR2: fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome)
• PCBD1: 6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)
• PCDH15: protocadherin 15
• PTEN: phosphatase and tensin homolog (mutated in multiple advanced cancers 1)
• RET: ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease)
• UROS: uroporphyrinogen III synthase (congenital erythropoietic porphyria)

[değiştir] Hastalıklar

Kromozom 10 üzerinde bulunan genlerle ilgili olan hastalıkların bazıları:

• Apert syndrome
• Beare-Stevenson cutis gyrata syndrome
• Charcot-Marie-Tooth disease
• Charcot-Marie-Tooth disease, type 1
• Charcot-Marie-Tooth disease, type 4
• Cockayne syndrome
• congenital erythropoietic porphyria
• Cowden syndrome
• Crouzon syndrome
• Jackson-Weiss syndrome
• multiple endocrine neoplasia type 2
• nonsyndromic deafness
• nonsyndromic deafness, autosomal recessive
• Pfeiffer syndrome
• porphyria
• tetrahydrobiopterin deficiency
• Usher syndrome
• Usher syndrome type I

Kromozomlar - İnsan kromozomlarıdeğiştir

Otozomlar

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Gonozomlar

X Kromozomu | Y Kromozomu