Aspartic acid

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Chemical structure of L-aspartic acid
Aspartic acid
Systematic (IUPAC) name
(2S)-2-aminobutanedioic acid
Identifiers
CAS number	56-84-8
PubChem	5960
Chemical data
Formula	C₄H₇N O₄
Mol. weight	133.10
Complete data

Aspartic acid (Asp, D), also known as aspartate, the name of its anion, is one of the 20 natural proteinogenic amino acids which are the building blocks of proteins.

As with each of the 20 natural amino acids, there are two abbreviations commonly used to designate aspartic acid: Asp (three letter) and D (one letter). The abbreviations signifying a choice of either aspartic acid or asparagine are Asx (three-letter) and B (one letter).^[1]

As its name indicates, aspartic acid is the carboxylic acid analog of asparagine. It is non-essential in mammals, and might serve as an excitatory neurotransmitter in the brain and is an excitotoxin. It is also a metabolite in the urea cycle, and participates in gluconeogenesis.

As a neurotransmitter, aspartic acid may provide resistance to fatigue and thus lead to endurance, although the evidence to support this idea is not strong.

[edit] References

^a IUPAC-IUBMB Joint Commission on Biochemical Nomenclature. Nomenclature and Symbolism for Amino Acids and Peptides. Recommendations on Organic & Biochemical Nomenclature, Symbols & Terminology etc.. Retrieved on September 28, 2005.

[edit] See also

Aspartate transaminase
Sodium poly(aspartate), a synthetic polyamide

[edit] External links

Links to external chemical sources

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Analogues of nucleic acids:	The 20 Common Amino Acids	Analogues of nucleic acids:
Alanine (dp) \| Arginine (dp) \| Asparagine (dp) \| Aspartic acid (dp) \| Cysteine (dp) \| Glutamic acid (dp) \| Glutamine (dp) \| Glycine (dp) \| Histidine (dp) \| Isoleucine (dp) \| Leucine (dp) \| Lysine (dp) \| Methionine (dp) \| Phenylalanine (dp) \| Proline (dp) \| Serine (dp) \| Threonine (dp) \| Tryptophan (dp) \| Tyrosine (dp) \| Valine (dp)